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A systematic literature search was performed across major biomedical and scientific databases, including PubMed, Scopus, and Web of Science, to identify relevant publications available up to May 2025

As it has been shown previously in this cohort that drinking 15-21 units per week and over leads to an increased risk of mortality[20], the cut-off of 15 was a reasonable choice, although we do not have sufficient data on consumption throughout the follow-up period to recommend changing the weekly limits